Hormone Replacement Therapy

For Women HRT is a treatment that can help manage symptoms like hot flashes and vaginal dryness by supplementing hormones like estrogen and progesterone. The most effective HRT plan is tailored to the individual and may involve systemic estrogen (pills, patches, gels) or low-dose vaginal options. For women with a uterus, a progestogen must be included to mitigate risks. It is crucial to discuss risks and benefits with a healthcare provider, as there are potential side effects.

  • Systemic therapy: Replaces estrogen/testosterone with pills, skin patches, gels, creams, pellets or sprays. It can treat various symptoms like hot flashes, night sweats, and mood changes. 
  • Low-dose vaginal therapy: Available as a cream, tablet, or ring. It is used to treat vaginal and urinary symptoms and has less systemic absorption. 
  • Progestogen: A progestin is prescribed with estrogen if you still have a uterus to protect against uterine cancer. 
  • Combination therapy: Some products combine estrogen and progestin in a single pill or patch. 
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  • Initiation: For the most favorable risk-to-benefit ratio, it’s often recommended to start HRT before age 60 or within 10 years of menopause. 
  • Risk assessment: Risks, such as an increased chance of blood clots, stroke, or heart attack, are higher for certain individuals (e.g., smokers, those with high blood pressure, diabetes, or obesity).  Personal and family history will be assessed.
  • Regular review: It is essential to have regular check-ins with a healthcare provider to ensure the benefits of the therapy still outweigh the risks. 
  • Tailored treatment: Every individual’s needs are different, so a personalized treatment plan is vital. 
  • Progestogen for uterus: If you have a uterus, you will need to take a progestogen along with estrogen to protect your uterine lining. 
  • Symptom relief: Effectively alleviates common menopause symptoms like hot flashes, night sweats, exhaustion, brain fogginess and vaginal dryness. 
  • Bone health: Can help prevent osteoporosis and reduce the risk of fractures. 
  • Other potential benefits: May improve mood, energy levels, and quality of life. 

It is crucial to consult a healthcare provider for a personalized assessment of risks and benefits before starting or changing any HRT regimen.

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